Guido Bocci Selected Research

Colorectal Neoplasms (Colorectal Cancer)

1/2018	Pharmacokinetic analysis of metronomic capecitabine in refractory metastatic colorectal cancer patients.
8/2017	Simultaneous, But Not Consecutive, Combination With Folinate Salts Potentiates 5-Fluorouracil Antitumor Activity In Vitro and In Vivo.
11/2016	Pharmacokinetics of metronomic chemotherapy: a neglected but crucial aspect.
9/2014	EGFR ligands as pharmacodynamic biomarkers in metastatic colorectal cancer patients treated with cetuximab and irinotecan.
1/2014	A new biometric tool for three-dimensional subcutaneous tumor scanning in mice.
1/2012	Population pharmacokinetic analysis of 5-FU and 5-FDHU in colorectal cancer patients: search for biomarkers associated with gastro-intestinal toxicity.
2/2010	Targeting vascular endothelial growth factor pathway in first-line treatment of metastatic colorectal cancer: state-of-the-art and future perspectives in clinical and molecular selection of patients.
10/2009	Metronomic 5-fluorouracil, oxaliplatin and irinotecan in colorectal cancer.
5/2008	5-fluorouracil pharmacokinetics predicts disease-free survival in patients administered adjuvant chemotherapy for colorectal cancer.
11/2006	Thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer and normal mucosa in patients.

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Guido Bocci Research Topics

Disease

60	Neoplasms (Cancer) 11/2023 - 05/2002
18	Breast Neoplasms (Breast Cancer) 12/2023 - 05/2002
12	Glioblastoma (Glioblastoma Multiforme) 03/2024 - 01/2018
12	Colorectal Neoplasms (Colorectal Cancer) 01/2018 - 09/2006
11	Anaplastic Thyroid Carcinoma 02/2020 - 04/2012
10	Thyroid Neoplasms (Thyroid Cancer) 01/2020 - 03/2007
7	Prostatic Neoplasms (Prostate Cancer) 12/2016 - 08/2009
7	Macular Degeneration (Age-Related Maculopathy) 01/2016 - 01/2007
5	Carcinoma (Carcinomatosis) 01/2022 - 10/2004
4	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 11/2023 - 01/2019
3	Melanoma (Melanoma, Malignant) 11/2023 - 10/2005
3	Brain Neoplasms (Brain Tumor) 01/2023 - 12/2012
3	Drug-Related Side Effects and Adverse Reactions 01/2022 - 10/2006
3	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2022 - 10/2011
3	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 02/2021 - 10/2006
3	Colonic Neoplasms (Colon Cancer) 01/2020 - 08/2017
3	Lymphoma (Lymphomas) 12/2018 - 10/2011
3	Neoplasm Metastasis (Metastasis) 01/2017 - 08/2009
3	Pancreatic Neoplasms (Pancreatic Cancer) 09/2012 - 09/2004
3	Endometriosis 12/2010 - 11/2003
2	Cardiovascular Diseases (Cardiovascular Disease) 12/2023 - 02/2017
2	Weight Loss (Weight Reduction) 11/2023 - 11/2006
2	Cancer Pain 10/2023 - 01/2020
2	Seizures (Absence Seizure) 01/2022 - 01/2022
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2018 - 02/2016
2	Triple Negative Breast Neoplasms 01/2016 - 12/2015
2	medullary Thyroid cancer 11/2014 - 02/2014
2	Hepatocellular Carcinoma (Hepatoma) 01/2014 - 11/2006
2	Infections 09/2013 - 04/2010
2	Pre-Eclampsia (Preeclampsia) 02/2013 - 06/2004
2	Neutropenia 12/2011 - 05/2002
1	Hematologic Neoplasms (Hematological Malignancy) 04/2024
1	Lung Neoplasms (Lung Cancer) 03/2024
1	Cardiotoxicity 12/2023
1	Opioid-Related Disorders (Opiate Addiction) 10/2023

Drug/Important Bio-Agent (IBA)

23	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2022 - 09/2004
12	Fluorouracil (Carac)FDA LinkGeneric 02/2021 - 06/2005
11	Cyclophosphamide (Cytoxan)FDA LinkGeneric 08/2023 - 10/2003
10	Paclitaxel (Taxol)FDA LinkGeneric 08/2023 - 05/2002
10	Irinotecan (Camptosar)FDA LinkGeneric 01/2020 - 09/2006
10	Tyrosine Kinase InhibitorsIBA 01/2018 - 09/2004
9	Biomarkers (Surrogate Marker)IBA 03/2024 - 06/2004
8	Bevacizumab (Avastin)FDA Link 03/2022 - 05/2007
8	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 03/2022 - 09/2004
7	Antineoplastic Agents (Antineoplastics)IBA 01/2023 - 10/2005
6	Vinorelbine (Navelbine)FDA LinkGeneric 05/2021 - 02/2016
5	ErbB Receptors (EGF Receptor)IBA 07/2016 - 09/2013
5	pyrimidineIBA 07/2016 - 02/2011
5	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 07/2016 - 09/2004
5	Proteins (Proteins, Gene)FDA Link 02/2014 - 10/2005
4	AntibodiesIBA 01/2023 - 11/2005
4	Thrombospondin 1IBA 03/2022 - 10/2003
4	Interleukin-8 (Interleukin 8)IBA 03/2022 - 12/2014
4	Sunitinib (Sutent)FDA Link 01/2019 - 05/2012
4	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 05/2018 - 09/2004
3	CalciumIBA 03/2024 - 01/2006
3	Valproic Acid (Depakote)FDA LinkGeneric 01/2023 - 01/2022
3	Anticonvulsants (Antiepileptic Drugs)IBA 01/2022 - 01/2020
3	Temozolomide (Temodar)FDA LinkGeneric 01/2022 - 06/2018
3	Celecoxib (Celebrex)FDA Link 02/2021 - 08/2009
3	LigandsIBA 01/2020 - 06/2004
3	pazopanib FDA Link 01/2019 - 04/2015
3	Topotecan (Hycamtin)FDA LinkGeneric 01/2019 - 04/2015
3	Gemcitabine FDA Link 01/2017 - 09/2004
2	Ion Channels (Ion Channel)IBA 12/2023 - 01/2020
2	2- (2- (2- (5- bromo- 2- methoxyphenyl)ethyl)- 3- fluorophenyl)- 4,5- dihydro- 1H- imidazoleIBA 11/2023 - 06/2018
2	Opioid Analgesics (Opioids)IBA 10/2023 - 01/2020
2	liposomal doxorubicin (Doxil)FDA Link 08/2023 - 02/2017
2	LithiumIBA 01/2023 - 01/2022
2	Alkylating AgentsIBA 01/2022 - 10/2005
2	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 01/2022 - 01/2021
2	ProdrugsIBA 01/2022 - 02/2021
2	lenvatinibIBA 01/2020 - 05/2018
2	Hormones (Hormone)IBA 01/2019 - 08/2009
2	Phosphotransferases (Kinase)IBA 01/2019 - 02/2014
2	MelanocortinsIBA 06/2018 - 01/2018
2	Cisplatin (Platino)FDA LinkGeneric 01/2017 - 10/2005
2	Dexamethasone (Maxidex)FDA LinkGeneric 12/2016 - 08/2009
2	Ranibizumab (Lucentis)FDA Link 01/2016 - 04/2013
2	4- chloro- N- (1,1,3- trioxo- 2,3- dihydrobenzo(d)isothiazol- 4- yl)benzamideIBA 11/2014 - 04/2012
2	AmidesIBA 11/2014 - 04/2012
2	Messenger RNA (mRNA)IBA 09/2013 - 11/2006
2	Daptomycin FDA Link 09/2013 - 04/2010
2	Cyclin D1IBA 09/2012 - 06/2011
2	Monoclonal AntibodiesIBA 05/2012 - 09/2004
2	Endothelial Growth FactorsIBA 02/2011 - 05/2002
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 10/2009 - 09/2006
2	DNA (Deoxyribonucleic Acid)IBA 08/2009 - 10/2005
2	Leucovorin (Folinic Acid)FDA Link 10/2006 - 09/2006
1	AldosteroneIBA 12/2023
1	Estrogens (Estrogen)FDA Link 12/2023
1	Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)IBA 11/2023
1	VemurafenibIBA 11/2023
1	Methadone (Dolophine)FDA LinkGeneric 10/2023

Therapy/Procedure

33	Drug Therapy (Chemotherapy) 04/2024 - 09/2006
23	Therapeutics 12/2023 - 05/2002
3	Radiotherapy 11/2021 - 01/2015
3	Castration 12/2016 - 05/2010
2	Heterologous Transplantation (Xenotransplantation) 08/2014 - 02/2011
2	Breast Implants (Breast Implant) 01/2014 - 10/2011